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Department of Statistics

Turning data into knowledge to solve real world problems

Shanpu Zhang

Professor
Dr. Shunpu Zhang
Department of Statistics
University of Nebraska - Lincoln
346D Hardin Hall North
Lincoln, NE 68583 0963

Office Phone: 402 472 8108
email: szhang3@unl.edu
Web Page:

 

Research Interest:

Bayes and empirical Bayes method; Nonparametric functional function; Nonparametric deconvolution; Statistical ecology; Bioinformatics (microarray data analysis; Pharmacokinetic (PK) and Pharmacodynamic (PD) modeling; Statistical methods in influenza virus genotypinge.

Selected publications

Wang, Y., Eskridge, K. M., and Zhang, S. (2008). Semiparametric mixed analysis on PK/PD Models using differential equations. Journal of Pharmacokinetics and Pharmacodynamics. 35(4): 443-63.

Wang, Y., Eskridge, K. M., Zhang, S., and Wang D. (2008). Using Spline-Enhanced Ordinary Differential Equations for PK/PD Model Development. Journal of Pharmacokinetics and Pharmacodynamics. Published online on Nov 07, 2008.

Zhang, S. and Karunamuni, R.J. (2008). Deconvolution Boundary Kernel Method in Nonparametric Density Estimation. Journal of Statistical Planning and Inference. doi:10.1016/j.jspi. 2008.10.021. Published online on Dec 12, 2008.

Jiao, S. and Zhang, S. (2008). The t-mixture model approach for detecting differentially expressed genes in microarrays. Functional & Integrative Genomics, 8: 181-186. Available at http://www.springerlink.com/content/whp223044833424u/.

Zhang, S. (2008). Improving detection of differentially expressed genes from microarray experiments using more efficient statistics, the local optimal fudge factor and a two-stage FDR correction. Chapter 11 in the book "Oligonucleotide Array Sequence", Nova Science Publishers (invited).

Lu, G, Zhang, S and Fang, X. (2008). An improved string composition method for sequence comparison. BMC Bioinformatics, 9 (Suppl 6): S15.

Jiao, S. and Zhang, S. (2008). On correcting the overestimation of the permutation-based false discovery rate estimator. Bioinformatics. 24(15):1655-1661; doi:10.1093/bioinformatics/btn310.

Karunamuni, R. J. and Zhang, S. (2008). Some improvements on a boundary corrected kernel density estimator. Probability and Statistics Letters, 78, 499-507.

Fang, X, Stroup, W., and Zhang, S. (2007). Improved Empirical Bayes Estimation in Group Testing Procedure for Small Proportions. Communications in Statistics, Theory and Methods, 36, 2937-2944.

Zhang, S. (2007). A comprehensive evaluation of SAM, the SAM R-package and a simple modification to improve its performance. BMC Bioinformatics, 8:230. Available at http://www.biomedcentral.com/1471-2105/8/230.

Zhang, S., Lu, G., Fang, X., and Donis, R. (2007). Multidimensional scaling and model-based clustering analyses for the clade assignments of the HPAI H5N1 viruses. Options for the Control of Influenza VI, International Medical Press. London: Blackwell.

Zhang, S. (2006). An Improved Nonparametric Approach for Detecting Differentially Expressed Genes with Replicated Microarray Data. Statistical Applications in Genetics and Molecular Biology 5.1. Available at: http://works.bepress.com/shunpu_zhang/1.